Down syndrome

DEVELOPMENTAL MILESTONE Crawl around 8 months rather than 5 Walk 21 months rather than 14 Children with Down syndrome has better understanding than the ability to speak. 10-45% either stutter or have rapid and irregular speech making it hard to understand spoken words. NEUROLOGICAL Most have mild IQ 50-70 Some with moderate 35-50 Some severe IQ 20-35 SENSES More than half of the population with Down syndrome has hearing and vision disorder. Chronic ear infection Hearing loss found in 50-90% of children with Down syndrome Strabismus 20-50% the two eyes do not move together. HEART 40% of newborn have congenital heart failure CANCER Increased risk of leukemia and testicular cancer Reduce risk of solid cancer due to du resale gene present on Che some 21. FERTILITY Males with Down syndrome usually do not father children due to problems with sperm development. While female fertility estimates at 30-50%